arXiv — NLP / Computation & Language · · 3 min read

MOOSE-Copilot: A Web-Based Interactive Assistant for Unified Exploratory and Fine-Grained Scientific Hypothesis Discovery

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Computer Science > Computation and Language

arXiv:2605.29475 (cs)
[Submitted on 28 May 2026]

Title:MOOSE-Copilot: A Web-Based Interactive Assistant for Unified Exploratory and Fine-Grained Scientific Hypothesis Discovery

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Abstract:Large language models (LLMs) show remarkable potential in scientific hypothesis discovery. However, existing approaches face two critical limitations: they treat divergent exploratory ideation and convergent fine-grained refinement as isolated tasks, and they operate autonomously with little to no human guidance. We present MOOSE-Copilot, the first unified framework to bridge this abstraction gap through a formalized human-AI interaction (HAII) protocol. Our system empowers scientists to steer the generative process via three explicit signals: initial blueprints, inter-stage routing, and regenerative feedback. Quantitative evaluations demonstrate that injecting these structured expert signals significantly outperforms purely autonomous baselines, establishing a performance ceiling under oracle guidance. Furthermore, to democratize this paradigm, we develop an intuitive web-based interface featuring interactive tree visualization. This explicitly eliminates the steep learning curve of complex command-line agentic tools, empowering interdisciplinary researchers to directly leverage, visually orchestrate, and accelerate end-to-end scientific breakthroughs.
Comments: Accepted to ACL 2026 (System Demonstrations)
Subjects: Computation and Language (cs.CL); Artificial Intelligence (cs.AI); Computational Engineering, Finance, and Science (cs.CE); Human-Computer Interaction (cs.HC)
Cite as: arXiv:2605.29475 [cs.CL]
  (or arXiv:2605.29475v1 [cs.CL] for this version)
  https://doi.org/10.48550/arXiv.2605.29475
arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Zonglin Yang [view email]
[v1] Thu, 28 May 2026 07:06:10 UTC (589 KB)
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