arXiv — NLP / Computation & Language · · 3 min read

ClinTraceBench: Source-Verifiable Longitudinal Clinical Reasoning over EHR-Derived Dialogues

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Computer Science > Computation and Language

arXiv:2609.01111 (cs)
[Submitted on 1 Sep 2026]

Title:ClinTraceBench: Source-Verifiable Longitudinal Clinical Reasoning over EHR-Derived Dialogues

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Abstract:Clinical LLM assistants must reason over multi-visit patient trajectories, yet whether the compact history representations used to scale them---retrieval, structured timelines, LLM summaries, agentic memory---preserve the longitudinal signal clinical reasoning needs has not been measured. We introduce ClinTraceBench: 385 MIMIC-IV-derived verified dialogues with event-ID provenance, a nine-task taxonomy (T1--T9), and L0--L4 deterministic + L5 human-audit validation (98.92\% agreement). We evaluate eight history representation strategies---a no-context floor, \textit{last-visit-only}, \textit{full-context}, BGE-M3 \textit{dense-retrieval}, two compression schemes, and two agentic-memory systems (\textit{Mem0}, \textit{A-Mem})---across four backbones (DeepSeek-V3, GPT-4o-mini, Haiku~4.5, Sonnet~4.6) on 6{,}271 questions: 32 cells, 200{,}672 predictions. Four findings: (SP4) a controlled T3 injection probe isolates compression-induced \textit{relation} loss---with the attribution sentence present \textit{before} construction, \textit{Mem0}, \textit{A-Mem} and \textit{llm-summary} still recover only 0--5.3\% of the injected positives; (SP1) compressed strategies pay an aggregation tax on multi-visit trends and cross-patient comparisons; (SP2) the blind-to-full gap spans $+29.8$~pp (GPT-4o-mini) to $+62.7$~pp (Haiku); (SP3) abstention scales non-monotonically with context length. On the Pareto frontier Haiku dominates Sonnet under \textit{full-context} (\$25.76 vs.\ \$106.21), inverting the ``biggest backbone wins'' heuristic.
Comments: Findings of EMNLP 2026
Subjects: Computation and Language (cs.CL)
Cite as: arXiv:2609.01111 [cs.CL]
  (or arXiv:2609.01111v1 [cs.CL] for this version)
  https://doi.org/10.48550/arXiv.2609.01111
arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Zhengyi Zhao [view email]
[v1] Tue, 1 Sep 2026 11:51:37 UTC (1,995 KB)
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