arXiv — NLP / Computation & Language · · 3 min read

Are LLMs Ready to Assist Physicians? PhysAssistBench for Interactive Doctor-Patient-EHR Assistance

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Computer Science > Computation and Language

arXiv:2606.18613 (cs)
[Submitted on 17 Jun 2026]

Title:Are LLMs Ready to Assist Physicians? PhysAssistBench for Interactive Doctor-Patient-EHR Assistance

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Abstract:The most plausible near-term role of medical LLMs is to assist rather than replace physicians, yet current evaluations often test isolated capabilities: clinical knowledge, EHR system interaction, or patient communication. Physician assistance instead requires coordinating these capabilities within the same interaction, where physicians issue underspecified requests, patients describe symptoms ambiguously, and EHR systems demand precise tool use. We introduce PhysAssistBench, a benchmark for interactive doctor-patient-EHR assistance. Built from real MIMIC-IV cases, PhysAssistBench uses a scalable pipeline to construct agentic patients: interactive, record-grounded agents that turn static EHR records into multi-turn clinical scenarios while preserving clinical factuality. PhysAssistBench provides a curated bilingual evaluation set of 1,296 manually reviewed and physician-validated turns. Experiments with leading LLMs show that current models remain unreliable in this setting, which exposes a key bottleneck for clinical LLMs: reliable assistance requires coordination across knowledge, communication, and systems, not isolated gains in any of them.
Comments: 34 pages with 8 figures
Subjects: Computation and Language (cs.CL); Artificial Intelligence (cs.AI)
Cite as: arXiv:2606.18613 [cs.CL]
  (or arXiv:2606.18613v1 [cs.CL] for this version)
  https://doi.org/10.48550/arXiv.2606.18613
arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Tianming Du [view email]
[v1] Wed, 17 Jun 2026 02:20:29 UTC (1,747 KB)
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