arXiv — NLP / Computation & Language · · 3 min read

Curation and Extraction of Drug-Related Entities from Reddit Platform

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Computer Science > Computation and Language

arXiv:2605.26445 (cs)
[Submitted on 8 Apr 2026]

Title:Curation and Extraction of Drug-Related Entities from Reddit Platform

View a PDF of the paper titled Curation and Extraction of Drug-Related Entities from Reddit Platform, by Zewei Wang and 4 other authors
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Abstract:Physicians learn primarily about illicit drugs from clinical overdose cases, limiting their understanding of real-world usage. Meanwhile, drug users share first-hand experiences online, offering insights into dosage and effects of drugs. To bridge this gap, we introduce ReDose (REddit Drug DOSe and Effect), a dataset of 6,435 Reddit posts on substance use. A board-certified toxicologist primarily annotated both the training and test sets, while two medical science students contributed to the test set, labeling DRUG, DOSE, and EFFECT entities. We benchmarked 6,267 annotations using BERT-based, large language model (LLM)-based, and Retrieval-Augmented Generation (RAG) models. BiomedBERT achieved an F1-score of 0.843 for DRUG, while Llama-3 70B outperformed GPT-4 (F1 = 0.79 vs. 0.72). EFFECT extraction remains challenging, with GPT-4 achieving a recall of 0.41. ReDose captures patient-curated narratives to advance medical data extraction from social media.
Comments: Accepted by IEEE International Conference on Healthcare Informatics (ICHI 2026)
Subjects: Computation and Language (cs.CL)
Cite as: arXiv:2605.26445 [cs.CL]
  (or arXiv:2605.26445v1 [cs.CL] for this version)
  https://doi.org/10.48550/arXiv.2605.26445
arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Zihan Xu [view email]
[v1] Wed, 8 Apr 2026 05:05:52 UTC (353 KB)
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