arXiv — NLP / Computation & Language · · 3 min read

Personalized State-Transition-Aware Memory for Clinical Agents

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Computer Science > Computation and Language

arXiv:2609.38490 (cs)
[Submitted on 29 Sep 2026]

Title:Personalized State-Transition-Aware Memory for Clinical Agents

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Abstract:Large language model (LLM) agents that reason over clinical records must track changes in a patient's state while preserving the history needed to understand them. Simply accumulating memories leaves it unclear which information still applies, whereas overwriting earlier memories can erase evidence needed to reconstruct treatment history and clinical trajectories. We introduce STAM, a state-transition-aware memory framework that records state changes as new clinical entries arrive. STAM combines semantic retrieval with typed clinical relations to identify affected memories, maintaining current information in Active and superseded or resolved information in History. At read time, a query-dependent gate selectively serves historical memory. Across four longitudinal clinical benchmarks, we evaluate STAM with downstream question answering, direct state-maintenance diagnostics, and comparisons at approximately matched context lengths.
Subjects: Computation and Language (cs.CL); Artificial Intelligence (cs.AI)
Cite as: arXiv:2609.38490 [cs.CL]
  (or arXiv:2609.38490v1 [cs.CL] for this version)
  https://doi.org/10.48550/arXiv.2609.38490
arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Maryam Haghifam [view email]
[v1] Tue, 29 Sep 2026 20:19:53 UTC (257 KB)
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