arXiv — NLP / Computation & Language · · 3 min read

Automated ICD Classification of Psychiatric Diagnoses: From Classical NLP to Large Language Models

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Computer Science > Computation and Language

arXiv:2605.21154 (cs)
[Submitted on 20 May 2026]

Title:Automated ICD Classification of Psychiatric Diagnoses: From Classical NLP to Large Language Models

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Abstract:Mental health has become a global priority, leading to a massive administrative burden in the coding of clinical diagnoses. This study proposes the automation of psychiatric diagnostic analysis by mapping free-text descriptions to the International Classification of Diseases (ICD) using Natural Language Processing (NLP) and Machine Learning (ML) techniques. Utilizing a specialized dataset of 145,513 Spanish psychiatric descriptions, various text representation paradigms were evaluated, ranging from classical frequency-based models (BoW, TF-IDF) to state-of-the-art Large Language Models (LLMs) such as e5\_large, BioLORD, and Llama-3-8B. Results indicate that transformer-based embeddings consistently outperform traditional methods by capturing implicit semantic cues and nuanced medical terminology. The e5\_large model, through end-to-end fine-tuning, achieved the highest performance with a $F1_{micro}$ score of 0.866. This research demonstrates that adapting LLMs to specific clinical nomenclature is essential for overcoming the challenges of ``long-tail'' label distributions and the inherent ambiguity of psychiatric discourse.
Subjects: Computation and Language (cs.CL); Artificial Intelligence (cs.AI); Machine Learning (cs.LG)
Cite as: arXiv:2605.21154 [cs.CL]
  (or arXiv:2605.21154v1 [cs.CL] for this version)
  https://doi.org/10.48550/arXiv.2605.21154
arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Fernando Ortega [view email]
[v1] Wed, 20 May 2026 13:26:05 UTC (339 KB)
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