arXiv — Machine Learning · · 3 min read

Multi-Modal Machine Learning for Breast Cancer Recurrence Prediction

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Computer Science > Machine Learning

arXiv:2606.02892 (cs)
[Submitted on 1 Jun 2026]

Title:Multi-Modal Machine Learning for Breast Cancer Recurrence Prediction

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Abstract:Breast cancer recurrence, a leading cause of long-term mortality among survivors, requires timely and accurate risk assessment to guide follow-up care and treatment planning. Traditional predictive models, often limited to either structured or unstructured data alone, struggle to capture the full clinical context. This study examines the impact of integrating multi-modal clinical data, including treatment records, pathology reports, and clinician notes, on recurrence prediction. By integrating a rule-based regular expression extraction mechanism with a rigorous precedence-based conflict reconciliation strategy, our approach effectively recovers definitive tumor characteristics from free-text pathology narratives to augment structured records. We also benchmark performance against commonly used feature sets from prior breast cancer studies to assess the added value of multi-modal integration. Single-source and multi-modal inputs are evaluated across a range of machine learning models. Results show that multi-modal integration consistently improves predictive accuracy compared to single-modal methods.
Comments: 33 pages, 10 figures
Subjects: Machine Learning (cs.LG)
Cite as: arXiv:2606.02892 [cs.LG]
  (or arXiv:2606.02892v1 [cs.LG] for this version)
  https://doi.org/10.48550/arXiv.2606.02892
arXiv-issued DOI via DataCite (pending registration)

Submission history

From: Jiahao Shao [view email]
[v1] Mon, 1 Jun 2026 21:06:07 UTC (844 KB)
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